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HEALTHCARE: Amgen (AMGN: Baa1/BBB+ neg/BBB): Q4 24 Results

HEALTHCARE

Very Positive: but only has one € 750m 2026 bond out of $60bn outstanding

  • Stock initially fell 3% in the after market as early-stage obesity drug AMG-513 was paused
  • Up 6% now as focus turns to breadth of sales growth
  • 10 products saw >10% growth
  • FY sales $33.4bn +19%
  • FCF $10.4bn vs $7.4bn 2023
  • Patent cliff is a real risk for Amgen with 20% (Prolia & Xgeva) losing exclusivity in 1Q25 and Enbrel & Otezla by '28/'29 (19% sales)
  • R&D 19.8% investing in pipeline
  • Debt fell $4.5bn for FY24; Debt/EBITDA 4.5x
  • Guidance 2025 Sales +4.7% at mid-point
  • Weight-Loss: MariTide is still being tested after Nov's disappointment. AMG-513 on hold.
  • Pipeline is significant aside from weight-loss drugs.
  • Last issued 2023. $3.5bn matures 2025.
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Very Positive: but only has one € 750m 2026 bond out of $60bn outstanding

  • Stock initially fell 3% in the after market as early-stage obesity drug AMG-513 was paused
  • Up 6% now as focus turns to breadth of sales growth
  • 10 products saw >10% growth
  • FY sales $33.4bn +19%
  • FCF $10.4bn vs $7.4bn 2023
  • Patent cliff is a real risk for Amgen with 20% (Prolia & Xgeva) losing exclusivity in 1Q25 and Enbrel & Otezla by '28/'29 (19% sales)
  • R&D 19.8% investing in pipeline
  • Debt fell $4.5bn for FY24; Debt/EBITDA 4.5x
  • Guidance 2025 Sales +4.7% at mid-point
  • Weight-Loss: MariTide is still being tested after Nov's disappointment. AMG-513 on hold.
  • Pipeline is significant aside from weight-loss drugs.
  • Last issued 2023. $3.5bn matures 2025.